chemicell
PEG DERIVATES

New PEGylation reagents from chemicell

chemicell offers new polyethylene glycol (PEG) derivates which are synthesized under pharmaceutical conditions in water without any organic solvents and without toxic agents. All PEG derivates are delivered as sterile aqueous solutions.

Application

The protection of biological macromolecules, peptides, antibodies, proteins, and oligonucleotides is of extreme importance in biological, immunological and pharmacological applications.

There is growing interest of PEG and its α- and/or ω-substituted derivates and the protection offered by the covalent attachment of PEG to target molecules. PEGylation has become the method of choice for the delivery of bio-pharmaceuticals.

Linear PEGs can offer one or two reactive groups that can bind with a functional group on the target molecule.

Advantages of PEGylation

  • Increased bioavailability
  • Increased blood circulation of the target biomolecule / drug
  • Shielding receptor-mediated uptake by the reticuloendothelial system (RES)
  • Shielding of antigenic and immunogenic epitopes
  • Preventing recognition and degradation by proteolytic enzymes
  • Increasing the apparent size of polypeptides, thus reducing the renal filtration and altering biodistribution
  • Optimized pharmacokinetics
  • Decreased immunogenicity
Description Structure Formula Product Number PEGMW (Da) Amount Price EURO Price US$ Product Information
Polyethylene glycol di-succinic acid
α,ω-Di-succinic acid poly-ethylene glycol Polyethylene glycol di-succinic acid PDS6-1
PDS6-5
6000 1 g
5 g
120
500
160
640
PDS8-1
PDS8-5
8000 1 g
5 g
120
500
160
640
PDS20-1
PDS20-5
20000 1 g
5 g
120
500
160
640
Polyethylene glycol succinic acid
α-Methoxy-ω-succinic acid polyethylene glycol Polyethylene glycol succinic acid PMS5-1
PMS5-5
5000 1 g
5 g
120
500
160
640
Polyethylene glycol di-2,4-dicarboxylate
α,ω-Di-1-ester benzene-2,4-dicarboxylate-polyethylene glycol Polyethylene glycol di-2,4-dicarboxylate PDT6-1
PDT6-5
6000 1 g
5 g
120
500
160
640
PDT8-1
PDT8-5
8000 1 g
5 g
120
500
160
640
PDT20-1
PDT20-5
20000 1 g
5 g
120
500
160
640
Polyethylene glycol mono-2,4-dicarboxylate
α-Methoxy-ω-1-ester benzene-2,4-dicarboxylate-polyethylene glycol Polyethylene glycol mono-2,4-dicarboxylate PMT5-1
PMT5-5
5000 1 g
5 g
120
500
160
640
Polyethylene glycol di-phosphate
α,ω-Di-phosphate polyethylene glycol Polyethylene glycol di-phosphate PDP6-1
PDP6-5
6000 1 g
5 g
120
500
160
640
PDP8-1
PDP8-5
8000 1 g
5 g
120
500
160
640
PDP20-1
PDP20-5
20000 1 g
5 g
120
500
160
640
Polyethylene glycol phosphate
α-Methoxy-ω-phosphate poly-ethylene glycol Polyethylene glycol phosphate PMP5-1
PMP5-5
5000 1 g
5 g
120
500
160
640
Polyethylene glycol di-Cibacron Blue
α,ω-di-Cibacron Blue polyethylene glycol PDC6-1
PDC6-5
6000 1 g
5 g
120
500
160
640
PDC8-1
PDC8-5
8000 1 g
5 g
120
500
160
640
PDC20-1
PDC20-5
20000 1 g
5 g
120
500
160
640
Polyethylene glycol Cibacron Blue
α-Methoxy-ω-Cibacron Blue polyethylene glycol PDC5-1
PDC5-5
5000 1 g
5 g
120
500
160
640
Polyethylene glycol di-fluorescein
α,ω-Di-fluorescein poly-ethylene glycol Polyethylene glycol di-fluorescein PDF6-1
PDF6-5
6000 100 mg
500 mg
110
440
145
580
PDF8-1
PDF8-5
8000 100 mg
500 mg
110
440
145
580
PDF20-1
PDF20-5
20000 100 mg
500 mg
110
440
145
580
Polyethylene glycol fluorescein
α-Methoxy-ω-fluorescein polyethylene glycol Polyethylene glycol fluorescein PMF5-1
PMF5-5
5000 100 mg
500 mg
110
440
145
580
Polyethylene glycol di-amine
α,ω-Di-amine polyethylene glycol Polyethylene glycol di-amine PDA6-1
PDA6-5
6000 1 g
5 g
120
500
160
640
PDA8-1
PDA8-5
8000 1 g
5 g
120
500
160
640
PDA20-1
PDA20-5
20000 1 g
5 g
120
500
160
640
Polyethylene glycol amine
α-Methoxy-ω-amine polyethylene glycol Polyethylene glycol amine PMA5-1
PMA5-5
5000 1 g
5 g
120
500
160
640
Polyethylene glycol di-Rhodamine
α,ω-Di-Rhodamine polyethylene glycol Polyethylene glycol di-Rhodamine PDR6-1
PDR6-5
6000 100 mg
500 mg
110
440
145
580
PDR8-1
PDR8-5
8000 100 mg
500 mg
110
440
145
580
PDR20-1
PDR20-5
20000 100 mg
500 mg
110
440
145
580
Polyethylene glycol Rhodamine
α-Methoxy-ω-Rhodamine polyethylene glycol Polyethylene glycol mono-Rhodamine PMR5-1
PMR5-5
5000 100 mg
500 mg
110
440
145
580
More information