This protocol describes a quick purification of IgG molecules from serum, ascites or cell culture supernatants with SiMAG-Protein A or SiMAG-Protein G.
Protein A / G are covalently coupled to a magnetic silica particles to provide an efficient method of purifying antibodies.
SiMAG-Protein A / G binds with high specifity to the Fc region of most IgG subclasses from different species.